cancer
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Clinical features •Should be distinguished from trichoepithelioma since the latter may be multiple and associated with Brooke-Spiegler syndrome & multiple familial trichoepitheliomas •Exceptional association with Birt-Hogg-Dubé syndrome •M=F •5th-7th decades •Presents as a solitary, slowly growing nodule particularly affecting the scalp, head & neck, trunk, extremities & genitalia in decreasing order of frequency Plaque-like variant (F>>M) Histological…
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Clinical features •Although often classified as periocular or extraocular, this has little merit since there is no difference between the two groups in terms of overall survival •Periocular tumors mostly arise from the meibomian glands and present as a mass in the upper eyelid •Extraocular tumors most often present on the head and neck although they may arise in a very wide variety of sites. …
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Clinical features •Very rare •M=F •Age range 18-91 •Axilla>>scalp, eyelid, ear, anogenital region, chest, lip & wrist •Slowly growing sometimes ulcerated nodule or plaque •Rarely develops in a nevus sebaceus or complicates a benign precursor apocrine tumor •Often slowly growing and fairly indolent although high grade variants are not uncommon •Metastases to lymph nodes (50%), lung and bone •Recurrence rate 28% •Median survival: 51.5 months •Nodal and distant…