cutaneous-lymphoma
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Definition •Leukemic variant of CTCL with a very poor prognosis •Erythroderma affecting 80% or more of the integument; often scaly, intensely pruritic; sometimes marked edema •Lymphadenopathy •Circulating Sézary cell count of >1000/sq mm. •CD4:CD8 of 10 or more • CD4+/CD7- of 40% or more •CD4+ve/CD26-ve of 30% or more •Variable loss of T-cell antigens •T-cell monoclonal population…
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Clinical features •May present with & without follicular mucinosis •May be accompanied (and often is) by syringotropic MF •Very rare & presents most commonly in middle-aged or elderly males •Face, scalp (often associated with alopecia) & neck, trunk or limbs •Eyebrow involvement is said to be typical •Intensely itchy, patches, plaques or grouped papules •Sometimes seen in tumor stage disease •Occasionally…
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Currently classified as a variant of mycosis fungoides overlapping with granulomatous mycosis fungoides. It has been postulated by some that the entity is a reflection of the site of involvement (axiallae & groins) rather than indicating a separate disease. Due to its rarity, further larger series are needed to substantiate this hypophysis. Clinical features •Exceedingly…
McKee Derm 