leukemia

Clinical features •Very rare aggressive acute leukemia •Very commonly affects the skin in addition to the blood and bone marrow; also, lymph nodes & spleen •B symptoms •Mostly affects the elderly •3M:1F •Head, trunk & extremities •Bruise-like or erythematous maculopapular lesions, nodules or plaques •Associations with myelodysplastic syndrome, myelomonocytic leukemia or AML Histological features . No epidermal involvement . Dermal +/- subcutaneous fat infiltrate . No angioinvasion or angiodestruction . Monotonous blast…