science
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Clinical features •Head (scalp), neck, limbs but can occur anywhere •Slowly grown sharply circumscribed flesh colored/erythematous or blue nodule or cystic nodule 0.5-3 cm diameter •Generally symptomatic but can be pruritic or tender •Mostly 3rd– 5th decades (3-93 years) •Slight predominance in females Histological features •Solid or cystic sharply defined nodule in dermis sometimes extending into subcutaneous fat •Eccrine (predominantly poroid & cuticular cells) & apocrine variants (association with a follicle, decapitation secretion & GCDFP-15+ve) •May overlap with poroma…
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A relatively common benign sweat gland tumor characterised by an admixture of epithelial & mesenchymal elements. Typically thought of an apocrine gland tumor. Some authors recognise an eccrine variant. In my experience, such tumors are exceptionally rare. Many tumors show an admixture of both elements. Mixed tumor of the skin is mostly associated with rearrangment…
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Clinical features •Presents as a small pigmented papule or nodule on sun-damaged skin •3m:1F •28-92 years (mean 70) •0.2-2.5 cm (mean 0.8) diameter •Head, extremities, trunk in descending order of frequency Rarely recurs Histological features •Well circumscribed nodular or multinodular growth pattern •Admixture of basaloid matrical, supramatricial & eosinophilic shadow cells with dendritic melanocytes. The ghost cell change is distinctive affecting…
McKee Derm 