sweat-gland-tumors
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Clinical features •Rare & may present in the dermis, subcutaneous fat or soft tissue •Cutaneous lesions present mostly in adolescents & young adults with a predilection for males •Firm to hard nodule 0.5-2.5 cm •Age range newborn-93 years •Soft tissue tumors are often much larger & present most often limbs & limb girdles with an equal sex incidence •Malignant myoepithelioma in the soft tissues is exceedingly rare and has a…
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Papillary eccrine adenoma & tubular apocrine adenoma are very similar and some authors combine the two entities under the umbrella term “tubular adenoma”. While this has merit, there are clinical differences. Papillary eccrine adenoma arises most often on the extremities and shows a marked predilection for black females (9F:1M). Tubular apocrine adenoma most commonly arises…
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Clinical features •Very rare benign tumor that shows a predilection for the distal extremities •4F:1M •Black> White races •Slowly growing, asymptomatic, flesh colored or pink nodule (0.5-4 cm diameter) Histological features •Circumscribed nodule composed of ducts & cysts embedded in a dense fibrous stroma sometimes associated with lymphoid aggregates/germinal centers •Ducts lined by double-layered epithelium- small inner, uniform cells with eosinophilic…
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Clinical features •Tender or painful, sharply delineated typically blue 1-3 cm dermal nodule nodule •Ventral skin, most on the upper half of the integument (head, neck & trunk) •Rarely multiple lesions 2nd-4th decade •Giant variant •Linear, Blaschkoid, variants •Autosomal dominant familial variant •May occur as part of the Brooke-Spiegler syndrome Histological features •Nodule/multiple blue encapsulated nodules in the…
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Clinical features •Head (scalp), neck, limbs but can occur anywhere •Slowly grown sharply circumscribed flesh colored/erythematous or blue nodule or cystic nodule 0.5-3 cm diameter •Generally symptomatic but can be pruritic or tender •Mostly 3rd– 5th decades (3-93 years) •Slight predominance in females Histological features •Solid or cystic sharply defined nodule in dermis sometimes extending into subcutaneous fat •Eccrine (predominantly poroid & cuticular cells) & apocrine variants (association with a follicle, decapitation secretion & GCDFP-15+ve) •May overlap with poroma…
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Clinical features •May present as an intraepidermal lesion (hidroacanthoma simplex, a dermal tumor (dermal duct tumor) or as both with epidermal continuity (poroma); some tumors overlap hidradenoma & poroma (poroid hidradenoma overlap) •Solitary skin colored, erythematous or pigmented, generally asymptomatic nodule with a predilection for the foot but it may occur just about anywhere •M=F…
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A relatively common benign sweat gland tumor characterised by an admixture of epithelial & mesenchymal elements. Typically thought of an apocrine gland tumor. Some authors recognise an eccrine variant. In my experience, such tumors are exceptionally rare. Many tumors show an admixture of both elements. Mixed tumor of the skin is mostly associated with rearrangment…
McKee Derm 