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Trichoepithelioma is a hamartoma comprising a basaloid/germinative component and a prominent perifolliclular sheath proliferation. It may present as a solitary lesion or as multiple, familial lesions in multiple familial trichoepithelioma (which is probably a variant of Brook-Spiegler syndrome) & Brook-Spiegler syndrome. Clinical features •Solitary trichoepithelioma presents as a flesh-colored papule or nodule (<1.0 cm) most…
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A rare benign tumor showing differentiation towards the infundibular portion of the pilosebaceous canal. Some authors postulate that it occupies a place miday between trichoepithelioma & trichofolliculoma. Clinical features •Presents as a usually solitary, soft to firm, yellowish or pink nodule or plaque measuring up to 0.5-1.5 cm in diameter & most often affecting adults…
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Clinical features •An uncommon hamartoma presenting most often on the face & scalp as a solitary dome-shaped papule or nodule measuring 0.5-1.0 cm diameter •Exceptionally multiple lesions may be present •Rarely lesions may present in the external auditory meatus, on the external genitalia, nasal vestibule, lip, trunk & arm •Single or multiple thread-like white vellus hairs (trichoids) may protrude from…
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Clinical features •Asymptomatic, slowly growing less than 1.0 cm white or yellow lesion with a predilection for the cheek, chin & forehead •Lesions are indurated and the extent is difficult to delineate clinically similar to microcystic adnexal carcinoma) •Asymptomatic •Does not ulcerate •Rarely multiple •Often associated with a central dell .4F=1M Histological features •Consists of narrow epithelial strands & keratocysts embedded in a…
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Clinical features •Rare autosomal dominant developmental abnormality of vellus hair follicles predominantly affecting children and young adults •Sporadic forms are also recognized •M=F •Present with numerous flesh-colored to pink papules (1-5 mm) on chest, abdomen or extensor limbs but can be widespread •May also present as a solitary lesion •In some patients, the condition arises in association with a variety of conditions…
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Sebaceous hyperplasia Clinical features •This is common and presents as single or commonly multiple, yellow dome-shaped umbilicated papule(s) (1-2 mm diameter) on face of the elderly but may occur on the chest, the caruncle, external genitalia & areola •M>F •Increased incidence with cyclosporine Histological features •Lobules drain into a dilated follicle •Lobules are increased in number but do not…
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Although most scalp nevi can be readily classified into the regular nevus subtypes- common, congenital, blue etc, exceptionally they may show features more commonly seen at “the socalled milk-line” sites. Some authors use the term “atypical nevus of the scalp”. Histological features •Junctional/compound •Large dyscohesive nests with retraction artifact, not restricted to the tips of…
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•The late Bernie Ackerman classified acquired melanocytic nevi into Miescher nevus which most commonly occurs on the face and Unna nevus which generally presents on or below the neck •Miescher nevus is typically dome-shaped •In Miescher nevus, the nevus is generally dermal, wedge shaped & extends into the reticular dermis •Unna nevus presents as an exophytic, light to dark brown, polypoid,…
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This is uncommon and presents clinically with a history of recent change in color of a common or less often congenital nevus causing concern for melanoma by the clinician. Some, but not all are probably deep penetrating and combined nevus variants. Others may represent follicular type-A cell nests. It is characterized by the presence of…
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This is a rare variant of melanocytic nevus, so-named because it shares some of the features of ancient schwannoma and not because of its age! It most often arises on the face of older patients as a flesh colored or erthematous nodule. Its importance is that it may be mistaken as melanoma by the unwary.…
McKee Derm 