Uncategorized
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Clinical features •Rare, aggressive variant of SCC •Should be distinguished from mucoepidermoid carcinoma •Head (particularly the face & scalp) & neck are most affected but acral lesions are documented in addition to tumors on the penis •Elderly patients •Presents as an indurated, erythematous raised plaque •Tumors often very thick at presentation •Recurrences are common & the tumor has significant metastatic…
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Clinical features •Rare variant of epidermoid cyst associated with HPV infection •Mostly adults and the face is most often affected followed by trunk & arms •Should be distinguished from HPV-associated epidermoid cyst which presents on the soles with a predilection for the Japanese Histological features •Infundibular cyst lined by acanthotic squamous epithelium showing marked hypergranulosis, hyperkeratosis & parakeratosis •Conspicuous, enlarged keratohyalin granules •Koilocytosis •Squamous eddies are often a prominent feature…
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Clinical features •Rare & may present in the dermis, subcutaneous fat or soft tissue •Cutaneous lesions present mostly in adolescents & young adults with a predilection for males •Firm to hard nodule 0.5-2.5 cm •Age range newborn-93 years •Soft tissue tumors are often much larger & present most often limbs & limb girdles with an equal sex incidence •Malignant myoepithelioma in the soft tissues is exceedingly rare and has a…
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Clinical features •Rare lesion which most often represents a reactive phenomenon •Classified into 5 categories. Histological features •As the name implies, arises from the acrosyringium •Arising from the epidermis are multiple thin anastomosing strands of epithelium showing focal ductal differentiation •The stroma is often myxoid & may containlymphocytes & plasma cells •Exceptionally may be accompanied/complicated by SCC
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Clinical features •Very rare condition most often presenting in children although a wide age range may be affected (birth-73 years) •Adult lesions may develop following trauma •Slight preponderance of females •Presents as a slowly growing blue/purple, papulo/nodule or plaque (3mm-11cm) with a predilection for the limbs particularly the palms & soles although other sites including the head/neck & trunk may be affected •In children,…
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Papillary eccrine adenoma & tubular apocrine adenoma are very similar and some authors combine the two entities under the umbrella term “tubular adenoma”. While this has merit, there are clinical differences. Papillary eccrine adenoma arises most often on the extremities and shows a marked predilection for black females (9F:1M). Tubular apocrine adenoma most commonly arises…
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Clinical features •Uncommon •Head & neck with predilection for the cheek but can present at a wide variety of sites where apocrine are normally found •Dome-shaped, translucent, bluish/purple/black cystic nodule measuring up to 1.0-1.5 cm •Giant variant •Occurrence in nevus sebaceus •Exceptionally described in the parotid gland (Achour et al, 2023) •M=F •Middle-aged; occasionally seen in children •Moll gland cyst (eyelid), may cause ptosis…
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Exceedingly rare. Most cases are misdiagnoses & represent metastases from breast or less often large intestine Clinical features •Exceedingly rare •Head & neck •Occasionally trunk & extremities •Middle aged-elderly •A similar tumor may present on the vulva •M=F •Firm dermal nodule or plaque •Recurrences- 70%, metastases- 57%, mortality- 70% Histological features •Most cases are misdiagnoses & represent metastases from breast or less often large…
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Clinical features •Trichoblastic carcinoma, sarcoma & carcinosarcoma •Exceedingly rare, most cases have arisen on the face & scalp of the elderly but may present at a wide variety of sites •Exceptional complicating nevus sebaceus •Average age 65 •M>F •Exceptionally familial/syndromic e.g. Brooke-Spiegler syndrome •Some authors divide tumors into subtypes- low-grade presenting predominantly on the face (with risk of recurrence but no metastatic potential) & high-grade presenting at a wide…
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Clinical features •Rare, generally presenting as a solitary, flesh-colored papule or nodule on the central face with a predilection for the nose •Often presents in children •Less commonly affected sites include the scalp, nipples, limbs & external genitalia •0.5-2.5 cm diameter •Giant variant •Non-syndromic •Not associated with Muir-Torre syndrome Histological features •Circumscribed dermal nodule with a…
McKee Derm 